UNC-1679 (UNC1679) | L3MBTL3 inhibitor

Chemical Structure : UNC-1679

UNC-1679 (UNC 1679, UNC1679)

Catalog No.: PC-70161Not For Human Use, Lab Use Only.

UNC-1679 (UNC1679) is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM.

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Biological Activity

UNC-1679 (UNC1679) is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM.
UNC-1679 maintains in vitro and cellular potencyshows improved selectivity against other MBT-containing proteins compares with UNC1215.

Physicochemical Properties

M.Wt	446.595
Formula	C27H34N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-ethylisoindolin-5-yl)-4-(4-(pyrrolidin-2-yl)piperidine-1-carbonyl)benzamide

References

1. James LI, et al. J Med Chem. 2013 Sep 26;56(18):7358-71.

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UNC-1679 (UNC 1679, UNC1679)

Biological Activity

Physicochemical Properties

References

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