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VCP ATPase Activator 1

Chemical Structure : VCP ATPase Activator 1

CAS No.:

VCP ATPase Activator 1 (VAA1)

Catalog No.: PC-22444Not For Human Use, Lab Use Only.

VCP ATPase Activator 1 (VAA1) is a small molecule, allosteric activator of valosin-containing protein (VCP)/p97 with EC50 of 4.1 uM, dose-dependently stimulates VCP ATPase activity up to 3-fold.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VCP ATPase Activator 1 (VAA1) is a small molecule, allosteric activator of valosin-containing protein (VCP)/p97 with EC50 of 4.1 uM, dose-dependently stimulates VCP ATPase activity up to 3-fold.

Physicochemical Properties

M.Wt 354.47
Formula C20H22N2O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-(2-(ethylthio)phenyl)-3-(1-oxoisoindolin-2-yl)butanamide

References

1. Jones NH, et al. Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2316892121.

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