| Cat. No. |
Product Name |
Information |
| PC-38873 |
Vudalimab
PD-1/CTLA-4 bispecific mAb
|
Vudalimab (XmAb 20717, XmAb 717) is a bispecific antibody that simultaneously targets immune checkpoint receptors PD-1 and CTLA-4 and is designed to promote tumor-selective T-cell activation. |
| PC-38872 |
Vixarelimab
Anti-OSMRβ mAb
|
Vixarelimab (KPL-716) is a fully-human monoclonal antibody that targets oncostatin M receptor beta (OSMRβ), which mediates signaling of interleukin-31 (IL-31) and oncostatin M (OSM), two key cytokines implicated in pruritus, inflammation and fibrosis. |
| PC-38871 |
Tusamitamab
Anti-CEACAM5 mAb
|
Tusamitamab is a monoclonal antibody anti-CEACAM5, component of monoclonal antibody-drug conjugate Tusamitamab ravtansine (SAR 408701). |
| PC-38870 |
Tarlatamab
DLL3/CD3 BiTE mAb
|
Tarlatamab (AMG 757) is a half-life extended bispecific T-cell engager (BiTE) molecule targeting delta-like ligand 3 (DLL3), a target that is selectively expressed in SCLC tumors, but with minimal normal tissue expression. |
| PC-38869 |
Recaticimab
Anti-PCSK9 mAb
|
Recaticimab (SHR-1209) is a humanized immunoglobulin G1 monoclonal antibody against PCSK9, showed robust LDL-C reduction in vivo. |
| PC-38868 |
Vopratelimab
Anti-ICOS (CD278) mAb
|
Vopratelimab (JTX-2011) is an agonist monoclonal antibody that binds to and activates ICOS, the Inducible T cell CO-Stimulator, a protein on the surface of certain T cells commonly found in many solid tumors. |
| PC-38867 |
Pimivalimab
Anti-PD-1 mAb
|
Pimivalimab (JTX-4014) is a fully human monoclonal antibody targeting PD-1, potentially resulting in restoration of anti-tumor immune response. |
| PC-38866 |
Penpulimab
Anti-PD-1 mAb
|
Penpulimab (AK 105) is a humanized anti-programmed cell death 1 (PD-1) monoclonal antibody. Isotype: IgG1-kappa. Anti-[human PDCD1 (programmed cell death 1, PD-1, PD1, CD279)], monoclonal antibody. |
| PC-38864 |
Pavurutamab
BCMA/CD3 BiTE antibody
|
Pavurutamab (AMG 701) is a half-life extended anti-BCMA BiTE (bispecific T-cell engager) recombinant antibody, induces selective cytotoxicity against BCMA-expressing MM cells (EC50=18.8 pM), T-cell activation, and cytokine release in vitro and in vivo. |
| PC-38863 |
Pacanalotamab
BCMA/CD3 BiTE antibody
|
Pacanalotamab (AMG420) is a bispecific T-cell engager (BiTE) antibody, binds BCMA (B-Cell Maturation Antigen) on MM cells and CD3 on T cells. |
| PC-38862 |
Omodenbamab
Anti-SpA mAb
|
Omodenbamab is an anti-SpA (Staphylococcal protein A) humanized monoclonal antibody. Isotype: IgG3-kappa. Anti-[Staphylococcus aureus SpA (Staphylococcal protein A)], human monoclonal antibody. |
| PC-38859 |
Dafsolimab
Anti-CD3E mAb
|
Dafsolimab is a recombinant anti-CD3E (CD3 epsilon) monoclonal antibody.
Isotype: IgG2B-kappa. |
