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Cat. No. Product Name Information
PC-35901

QO IIR

COMT inhibitor

QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM.
PC-35791

Nebicapone

COMT inhibitor

Nebicapone (BIA 3-202, BIA3-202) is a potent, long-acting, reversible and competitive peripheral inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 3.7 nM for rat brain COMT, much less potent for liver COMT with IC50 of 696 nM.
PC-35459

Neluxicapone

COMT inhibitor

Neluxicapone is a potent, selective inhibitor of catechol-O-methyltransferase (COMT)..
PC-45228

Tolcapone

COMT inhibitor

Tolcapone (Ro 40-7592) selective, potent and reversible nitrocatechol-type inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 700 nM.
PC-23347

OR486

COMT inhibitor

OR486 (3,5-Dinitrocatechol, OR-486) is a potent, selective catechol-O-methyltransferase (COMT) inhibitor with IC50 of 12 nM.

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