| Cat. No. |
Product Name |
Information |
| PC-62067 |
NCGC 00067819
CREB activator
|
NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay. |
| PC-61256 |
Naphthol AS-E
KIX-KID inhibitor
|
Naphthol AS-E is a cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM). |
| PC-61254 |
XX-650-23
|
XX-650-23 is a small molecule inhibitor of CREB, blocks CREB/CBP interaction (IC50=3.2 uM) and disrupts CREB-driven gene expression. |
| PC-70246 |
KG-501
CREB-CBP inhibitor
|
A small-molecule antagonist of CREB-CBP interaction, inhibits the cAMP-dependent activation of cellular genes via CREB. |
| PC-21905 |
ATF3W-aeg peptide
ATF3 inhibitor
|
ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages. |
| PC-38619 |
CREB inhibitor 666-15
CREB1 inhibitor
|
CREB inhibitor 666-15 is a potent and selective inhibitor of CREB-mediated gene transcription with IC50 of 81 nM, potently inhibits cancer cell growth without harming normal cells. |
| PC-72794 |
Artepillin C
CREB/CRTC2 inhibitor
|
Artepillin C (CREB-CRTC2 inhibitor APC) is an inhibitor of CREB/CRTC2 interaction (IC50=24.5 uM), dissociates the CREB/CRTC2 complex, directly binds to CREB with Kd of 3.2 uM). |
