| Cat. No. |
Product Name |
Information |
| PC-60245 |
Avacopan
C5aR inhibitor
|
Avacopan (CCX-168, CCX168) is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM. |
| PC-45882 |
BCX-1470 methanesulfonate
Factor D/C1s inhibitor
|
BCX-1470 methanesulfonate is a potent serine protease inhibitor that inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM). |
| PC-45881 |
BCX-1470
Factor D/C1s inhibitor
|
BCX-1470 (BCX1470) is a serine protease inhibitor that inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM). |
| PC-25087 |
Refinicopan
Factor D inhibitor
|
Refinicopan is a potent, selective complement factor D inhibitor. |
| PC-25057 |
INF004
C5aR antagonist
|
INF004 is a potent, selective complement factor C5a receptor antagonist with IC50 of <10 nM. |
| PC-25056 |
Izicopan
C5aR antagonist
|
Izicopan (Compound INF052) is a potent, selective complement factor C5a receptor antagonist with IC50 of <10 nM. |
| PC-24490 |
Zilucoplan
Complement C5 inhibitor
|
Zilucoplan (RA101495) is a potent, selective macrocyclic peptide inhibitor of complement C5, binds to C5 with high affinity and specificity, prevents the cleavage of C5 into complement components C5a and C5b. |
| PC-24190 |
Factor D inhibitor compound II
Factor D inhibitor
|
Factor D inhibitor compound II is a potent, selective complement factor D inhibitor with IC50 of <1 uM, Patent WO2019195720 A1 (compound II). |
| PC-24189 |
Tarvicopan hydrochloride
Factor D inhibitor
|
Tarvicopan hydrochloride is a potent, selective complement factor D inhibitor. |
| PC-24188 |
Tarvicopan
Factor D inhibitor
|
Tarvicopan is a potent, selective complement factor D inhibitor. |
| PC-24142 |
Lanoracopan
Factor B inhibitor
|
Lanoracopan is a potent complement factor B inhibitor with IC50 of 1.2 uM. |
| PC-21966 |
SB290157 trifluoroacetate
C3aR inhibitor
|
SB290157 (SB 290157) trifluoroacetate is a potent, selective nonpeptide antagonist of anaphylatoxin C3a receptor (C3aR) with IC50 of 200 nM. |
