Cat. No. |
Product Name |
Information |
PC-42684 |
T0901317
LXR agonist
|
T0901317 (TO901317) is a potent, high affinity LXR agonist (EC50=50 nM, Kd are 7 and 22 nM for LXR-α and LXR-β respectively). |
PC-45108 |
SR9243
LXR inverse agonist
|
SR9243 is a potent LXR inverse agonist that inhibits LXR activation by enhancing LXR-corepressor recruitment. |
PC-42687 |
LXR-623
LXR agonist
|
LXR-623 (WAY 252623) is a clinically viable, highly brain-penetrant LXRα-partial/LXRβ-full agonist with binding Ki of 33 nM/248 nM, respectively. |
PC-24298 |
LXRα agonist 40
LXRα agonist
|
LXRα agonist 40 is a potent, specific agonist of transcription factor liver X receptor alpha (LXRα) with EC50 of 42 nM in TR-FRET assays, 6.3 fold selective over LXRβ activation. |
PC-23926 |
Inotodiol
LXRβ agonist
|
Inotodiol (CE9A215) is a lanostane-type triterpenoid compound isolated from the sclerotia of Inonotus obliquus, a selective LXRβ agonist with EC50 of <10 nM, shows potent anti-allergic and anti-inflammatory effects. |
PC-23680 |
PFM046
LXR antagonist
|
PFM046 is a potent antagonist of liver X receptors (LXRs) with IC50 of 2.04 μM for LXRα and 1.58 μM for LXRβ. |