Cat. No. |
Product Name |
Information |
PC-24178 |
PCSK9 inhibitor 3f
PCSK9 inhibitor
|
PCSK9 inhibitor 3f is a small molecule, orally bioavailable inhibitor of PCSK9 that antagonizes PCSK9-LDLR interaction with IC50 of 537 nM. |
PC-22461 |
E28362
PCSK9 inhibitor
|
E28362 is a novel small-molecule PCSK9 inhibitor, effectively binds to PCSK9 (SPR KD=14.8 uM) and disrupts the PCSK9-LDLR interaction, promotes the degradation of PCSK9 via the ubiquitin-proteasome pathway. |
PC-21266 |
NYX-1492
PCSK9 inhibitor
|
NYX-1492 is a small molecule PCSK9 inhibitor, blocks PCSK9 binding with the LDLR, attenuates inflammation in vascular cells and tissue-engineered blood vessels (TEBVs). |