| Cat. No. |
Product Name |
Information |
| PC-21563 |
INS018_055
TNIK inhibitor
|
INS018_055 (INS018-055) a selective small-molecule TRAF2- and NCK-interacting kinase (TNIK) inhibitor with Kd value of 4.32 nM and IC50 of 31 nM, inhibits TGF-β-induced α-SMA protein expression in MRC-5 cells with IC50 of 27.14 nM. |
| PC-36010 |
TNIK inhibitor X
TNIK inhibitor
|
TNIK inhibitor X is a potent inhibitor of Traf2- and Nck-interacting kinase (TNIK) (in vitro enzyme IC50=9 nM) with a reasonable selectivity over 30-folds against the majority of a panel of 50 kinases profiled. |
| PC-36009 |
KY-05009
TNIK inhibitor
|
KY-05009 (KY05009) is a potent, ATP-competitive inhibitor of Traf2- and Nck-interacting kinase (TNIK) with Ki of 100 nM. |
| PC-60644 |
PF-794
TNIK inhibitor
|
PF-794 (PF794) is a potent, specific and ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with IC50 of 39 nM in cell-free assays. |
| PC-42270 |
NCB-0846
TNIK inhibitor
|
NCB-0846 (NCB0846) is the first orally available, small-molecule TNIK inhibitor with IC50 of 21 nM. |
| PC-49469 |
TNIK inhibitor OBD9
TNIK inhibitor
|
OBD9 is a small molecule TNIK inhibitor that blocks Wnt/beta-catenin signaling at the final step of transcriptional activation, suppresses colorectal cancer growth by interfering with the Wnt signaling pathway. |
