TNIK (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21563	INS018_055 TNIK inhibitor	INS018_055 (INS018-055) a selective small-molecule TRAF2- and NCK-interacting kinase (TNIK) inhibitor with Kd value of 4.32 nM and IC50 of 31 nM, inhibits TGF-β-induced α-SMA protein expression in MRC-5 cells with IC50 of 27.14 nM.
PC-49469	TNIK inhibitor OBD9 TNIK inhibitor	OBD9 is a small molecule TNIK inhibitor that blocks Wnt/beta-catenin signaling at the final step of transcriptional activation, suppresses colorectal cancer growth by interfering with the Wnt signaling pathway.
PC-36010	TNIK inhibitor X TNIK inhibitor	TNIK inhibitor X is a potent inhibitor of Traf2- and Nck-interacting kinase (TNIK) (in vitro enzyme IC50=9 nM) with a reasonable selectivity over 30-folds against the majority of a panel of 50 kinases profiled.
PC-36009	KY-05009 TNIK inhibitor	KY-05009 (KY05009) is a potent, ATP-competitive inhibitor of Traf2- and Nck-interacting kinase (TNIK) with Ki of 100 nM.
PC-60644	PF-794 TNIK inhibitor	PF-794 (PF794) is a potent, specific and ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with IC50 of 39 nM in cell-free assays.
PC-42270	NCB-0846 TNIK inhibitor	NCB-0846 (NCB0846) is the first orally available, small-molecule TNIK inhibitor with IC50 of 21 nM.

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