| Cat. No. |
Product Name |
Information |
| PC-42449 |
OSI-930
c-Kit inhibitor
|
A potent, orally active, dual inhibitor of c-Kit and VEGFR-2 (KDR) with IC50 of 15 nM and 9 nM, respectively. |
| PC-42455 |
Masitinib mesylate
c-Kit/PDGFR inhibitor
|
Masitinib (AB-1010) mesylate is a potent tyrosine kinase inhibitor targeting c-Kit and PDGFR with IC50 of 0.15 and 0.05 uM in cell based assays. |
| PC-42454 |
Masitinib
c-Kit/PDGFR inhibitor
|
Masitinib (AB1010) is a potent tyrosine kinase inhibitor targeting c-Kit and PDGFR with IC50 of 0.15 and 0.05 uM in cell based assays. |
| PC-45100 |
Sitravatinib
Multikinase inhibitor
|
Sitravatinib (MGCD-516) is a broad spectrum small molecule inhibitor that blocks a wide array of RTKs known to be amplified/overexpressed in sarcomas, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl (IC50=1.5-30 nM). |
| PC-42451 |
Amuvatinib
c-Kit inhibitor
|
Amuvatinib (MP-470) is a potent RTK inhibitor that effectively inhibits c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
| PC-23095 |
Labuxtinib
c-Kit inhibitor
|
Labuxtinib is a small molecule inhibitor c-Kit kinase. |
| PC-21781 |
BLU-808
c-Kit inhibitor
|
BLU-808 is a potent and selective wt c-KIT inhibitor, potently inhibits c-KIT–dependent phosphorylation and proliferation with IC50 values in the sub-nanomolar and nanomolar range, respectively. |
