Cat. No. |
Product Name |
Information |
PC-73407 |
Bezuclastinib
mutated KIT inhibitor
|
Bezuclastinib (CGT9486, PLX9486) is a potent, selective tyrosine kinase inhibitor (TKI) targeting mutated KIT and demonstrating potent activity in vitro against primary exon 9 and 11 mutations, as well as secondary exon 17 and 18 mutations. |
PC-62536 |
CHMFL-KIT-031
|
CHMFL-KIT-031 is a highly selective KIT kinase primary V559D mutant inhibitor with IC50/Kd of 28/266 nM, 10-20 fold selectivity over KIT wt. |
PC-60152 |
KBP-7018 hydrochloride
|
A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively. |
PC-60151 |
KBP-7018
|
A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively. |
PC-42389 |
ISCK03
|
A specific c-Kit inhibitor that inhibits c-kit phosphorylation in vitro and
SCF-induced c-kit phosphorylation in human melanoma cells. |
PC-42455 |
Masitinib mesylate
|
A potent tyrosine kinase inhibitor targeting c-Kit and PDGFR with IC50 of 0.15 and 0.05 uM in cell based assays. |