Cat. No. |
Product Name |
Information |
PC-22945 |
M64HCl
FAK activator
|
M64HCl is a specific small molecule, water-soluble focal adhesion kinase (FAK) activator, interacts directly with the FAK kinase domain to activate FAK, induces epithelial sheet migration in vitro, and stimulates gut mucosal wound healing in vivo. |
PC-22876 |
FAK inhibitor E2
FAK inhibitor
|
FAK inhibitor E2 is a potent selective FAK inhibitor with IC50 of 3.58 nM, inhibits FAK downstream signaling cascades (e.g., Src and AKT), induces cytotoxic autophagy and inhibits ovarian cancer metastasis and growth. |
PC-22150 |
PF-719
Pyk2 inhibitor
|
PF-719 (PF719) is a potent, selective Pyk2 inhibitor with IC50 of 17 nM, displays 25-fold selectvity over FAK (IC50=469 nM). |