| Cat. No. |
Product Name |
Information |
| PC-62799 |
PF-4618433
Pyk2 inhibitor
|
PF-4618433 (PF4618433) is a highly potent, selective PYK2 inhibitor with IC50 of 637 nM, promotes osteogenesis of hMSC cultures. |
| PC-62798 |
Pyk2-IN-25a
Pyk2 inhibitor
|
Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM). |
| PC-61370 |
Conteltinib
FAK inhibitor
|
CT-707 (Conteltinib) is a novel multikinase inhibitor targeting FAK (IC50=1.6 nM), ALK and Pyk2, exerts synergistic antitumor effects against hepatocellular carcinoma in vitro and in vivo. |
| PC-70128 |
OXA-11
FAK inhibitor
|
OXA-11 is a potent and selective inhibitor of FAK phosphorylation with biochemical IC50 of 1.2 pM (pFAK Y397), cellular IC50 of 1 nM. |
| PC-60275 |
BI-853520
PTK2/FAK inhibitor
|
Ifebemtinib (BI 853520, IN10018) is potent, highly selective and orally active inhibitor of PTK2/FAK with IC50 of 1 nM in cell-free assays. |
| PC-45578 |
TAS-301
FAK inhibitor
|
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin. |
| PC-42177 |
GSK2256098
FAK inhibitor
|
GSK2256098 (GTPL-7939) is a potent, selective, reversible and ATP-competitive inhibitor of FAK kinase with Ki of 0.4 nM. |
| PC-42601 |
PF-562271
FAK/Pyk2 inhibitor
|
PF-562271 (VS-6062) is a potent, selective, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 14 nM, respectively. |
| PC-42600 |
PF-562271 besylate
FAK/Pyk2 inhibitor
|
A potent, selective, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 14 nM, respectively. |
| PC-42602 |
PF-573228
FAK inhibitor
|
PF-573228 is a potent, selective, ATP-competitive FAK inhibitor with IC50 of 4 nM. |
| PC-25557 |
THY-10A62
FAK inhibitor
|
THY-10A62 is a potent small molecule inhibitor of Focal adhesion kinase (FAK) with IC50 of 12 nM, has IC50 of 2.39 μM and 10.07 μM against the liver cancer cell lines YY8103 and SMMC7721, respectively. |
| PC-25159 |
FAK inhibitor E10
FAK inhibitor
|
FAK inhibitor E10 is a potent and highly selective FAK inhibitor with IC50 of 2.55 nM. |
