| Cat. No. |
Product Name |
Information |
| PC-62800 |
PF-431396
FAK/Pyk2 inhibitor
|
PF-431396 is a highly potent, dual PYK2/FAK inhibitor with IC50 of 11 and 2 nM, respectively, promotes osteogenesis of hMSC cultures. |
| PC-62799 |
PF-4618433
Pyk2 inhibitor
|
PF-4618433 (PF4618433) is a highly potent, selective PYK2 inhibitor with IC50 of 637 nM, promotes osteogenesis of hMSC cultures. |
| PC-62798 |
Pyk2-IN-25a
Pyk2 inhibitor
|
Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM). |
| PC-61370 |
Conteltinib
FAK inhibitor
|
CT-707 (Conteltinib) is a novel multikinase inhibitor targeting FAK (IC50=1.6 nM), ALK and Pyk2, exerts synergistic antitumor effects against hepatocellular carcinoma in vitro and in vivo. |
| PC-70128 |
OXA-11
FAK inhibitor
|
OXA-11 is a potent and selective inhibitor of FAK phosphorylation with biochemical IC50 of 1.2 pM (pFAK Y397), cellular IC50 of 1 nM. |
| PC-60275 |
BI-853520
PTK2/FAK inhibitor
|
Ifebemtinib (BI 853520, IN10018) is potent, highly selective and orally active inhibitor of PTK2/FAK with IC50 of 1 nM in cell-free assays. |
| PC-45578 |
TAS-301
FAK inhibitor
|
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, inhibits PDGF-induced tyrosine phosphorylation of both FAK and paxillin. |
| PC-42177 |
GSK2256098
FAK inhibitor
|
GSK2256098 (GTPL-7939) is a potent, selective, reversible and ATP-competitive inhibitor of FAK kinase with Ki of 0.4 nM. |
| PC-42601 |
PF-562271
FAK/Pyk2 inhibitor
|
PF-562271 (VS-6062) is a potent, selective, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 14 nM, respectively. |
| PC-42600 |
PF-562271 besylate
FAK/Pyk2 inhibitor
|
A potent, selective, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 14 nM, respectively. |
| PC-42602 |
PF-573228
FAK inhibitor
|
PF-573228 is a potent, selective, ATP-competitive FAK inhibitor with IC50 of 4 nM. |
| PC-25664 |
VS-4718
FAK inhibitor
|
VS-4718 (PND-1186) is a potent, highly-specific and reversible inhibitor of FAK with IC50 of 1.5 nM, promotes tumor cell apoptosis. |
