| Cat. No. |
Product Name |
Information |
| PC-72514 |
AXKO-0046
LDHB inhibitor
|
AXKO-0046 (AXKO0046) is the first highly selective, small molecule inhibitor of human lactate dehydrogenase B (LDHB), exhibits uncompetitive LDHB inhibition with EC50 of 42 nM. |
| PC-62683 |
LDHA-IN-104
LDHA inhibitor
|
LDHA-IN-104 is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.87 uM, less potent for LDHB (IC50=6.9 uM). |
| PC-62049 |
FX-11
LDHA inhibitor
|
FX-11 (LDHA inhibitor FX11) is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehydrogenase A (LDHA) with Ki of 50 nM (LDHA subunit M), less potent for LDHB or pLDH. |
| PC-61222 |
GSK 2837808A
LDHA inhibitor
|
GSK 2837808A is a potent, specific, NADH-competitive lactate dehydrogenase-A (LDH-A) inhibitor with IC50 of 2.6 nM, >10-fold selectivity over LDHB. |
| PC-42245 |
GNE-140 racemate
Lactate dehydrogenase inhibitor
|
GNE-140 racemate is the racemate of GNE-140, a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively. |
| PC-42247 |
(S)-GNE-140
|
The less active enantiomer of GNE-140, inhibits LDHA activity (18-fold less potent that (R)-GNE-140). |
| PC-42246 |
(R)-GNE-140
Lactate dehydrogenase inhibitor
|
(R)-GNE-140 (GNE-140) is a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively. |
| PC-23051 |
Nedosiran Sodium
LDH RNAi
|
Nedosiran sodium is a GalNAc-dsRNA conjugated RNA interference agent designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme, the enzyme responsible for the common, final step of oxalate production in all three genetic subtypes of primary hyperoxaluria (PH). |
| PC-23017 |
LDH-IN-1
LDH inhibitor
|
LDH-IN-1 (LDH inhibitor 63) is a potent, selective and cell-active lactate dehydrogenase (LDH) inhibitor with IC50 of 32 nM/27 nM for LDHA/LDHB respectively. |
