| Cat. No. |
Product Name |
Information |
| PC-35955 |
LY2623091
MR antagonist
|
LY2623091 (LY-2623091) is an orally administered mineralocorticoid receptor antagonist for the treatment of essential hypertension and chronic kidney disease. |
| PC-35939 |
KBP-5074
MR antagonist
|
KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease. |
| PC-35937 |
Apararenone
MR antagonist
|
Apararenone (MT-3995) is a highly selective and potent, nonsteroidal mineralocorticoid receptor (MR) antagonist with Ki of 104 nM, >360-fold selectivity over GR,AR,PR and ER receptors. |
| PC-63433 |
Finerenone
MR antagonist
|
Finerenone (BAY 94-8862) is a potent, selective, orally available mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM. |
| PC-62592 |
AZD9977
MR modulator
|
Balcinrenone (AZD9977) is a novel, first-in-class, selective and oral mineralocorticoid receptor (MR) modulator with pKi of 7.5, shows little to no affitnity for GR, PR and AR (pIC50<5.5). |
| PC-61848 |
PF-03882845
MR antagonist
|
PF-03882845 (PF-3882845) is highly potent, selective, nonsteroidal, orally bioavailable Mineralocorticoid receptor (MR, MLR) antagonist with IC50 of 4.5 nM. |
| PC-60751 |
DSR-71167
MR antagonist
|
DSR-71167 is a potent, selective mineralocorticoid receptor (MR) antagonist (IC50=0.26 uM) with carbonic anhydrase inhibitory activity (IC50=19 uM). |
| PC-60739 |
CS-3150
MLR antagonist
|
CS-3150 (Esaxerenone, XL-550) is a highly potent, selective and orally active non-steroidal mineralocorticoid receptor antagonist with IC50 of 9.4 nM. |
