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Request The Product List ofMineralocorticoid Receptor (MLR) Mineralocorticoid Receptor (MLR)

Cat. No. Product Name Information
PC-35955

LY2623091

MR antagonist

LY2623091 (LY-2623091) is an orally administered mineralocorticoid receptor antagonist for the treatment of essential hypertension and chronic kidney disease.
PC-35939

KBP-5074

MR antagonist

KBP-5074 (KBP5074, Ocedurenone) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.
PC-35937

Apararenone

MR antagonist

Apararenone (MT-3995) is a highly selective and potent, nonsteroidal mineralocorticoid receptor (MR) antagonist with Ki of 104 nM, >360-fold selectivity over GR,AR,PR and ER receptors.
PC-63433

Finerenone

MR antagonist

Finerenone (BAY 94-8862) is a potent, selective, orally available mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM.
PC-62592

AZD9977

MR modulator

Balcinrenone (AZD9977) is a novel, first-in-class, selective and oral mineralocorticoid receptor (MR) modulator with pKi of 7.5, shows little to no affitnity for GR, PR and AR (pIC50<5.5).
PC-61848

PF-03882845

MR antagonist

PF-03882845 (PF-3882845) is highly potent, selective, nonsteroidal, orally bioavailable Mineralocorticoid receptor (MR, MLR) antagonist with IC50 of 4.5 nM.
PC-60751

DSR-71167

MR antagonist

DSR-71167 is a potent, selective mineralocorticoid receptor (MR) antagonist (IC50=0.26 uM) with carbonic anhydrase inhibitory activity (IC50=19 uM).
PC-60739

CS-3150

MLR antagonist

CS-3150 (Esaxerenone, XL-550) is a highly potent, selective and orally active non-steroidal mineralocorticoid receptor antagonist with IC50 of 9.4 nM.

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