| Cat. No. |
Product Name |
Information |
| PC-26059 |
CN-716 hydrochloride
ZIKV NS3 protease inhibitor
|
CN-716 hydrochloride is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26058 |
CN-716
ZIKV NS3 protease inhibitor
|
CN-716 is a covalent, dipeptide boronic acid inhibitor of ZIKV NS3 protease catalytic site with IC50 of 0.5 uM. |
| PC-26057 |
IRBM-Z-2
ZIKV NS3 protease inhibitor
|
IRBM-Z-2 is a potent, non-competitive, allosteric inhibitor of ZIKV NS3 protease with binding KD of 21 nM (ZIKV NS2B-NS3 protease) and biochemical IC50 of 42 nM, potently inhibits both ZIKV viral replication (IC50=25 nM) and infectivity of ZIKV (CPE IC50=16 nM). |
| PC-26056 |
IRBM-Z-1
ZIKV NS3 protease inhibitor
|
IRBM-Z-1 is a non-competitive allosteric inhibitor of ZIKV NS3 protease with IC50 of 1.8 uM (wt NS2B-NS3 protease), exhibits ZIKV antiinfectivity activity in cell culture assays with EC50 of 6.25 uM. |
| PC-25193 |
CAPCA-1
CEN inhibitor
|
CAPCA-1 (Cpmpound B) a highly potent cap-dependent endonuclease (CEN) inhibitor, shows broad-spectrum antiviral activity against bunyavirus including Lassa virus (LASV), lymphocytic choriomeningitis virus (LCMV), and Influenza viruses. |
| PC-25136 |
RA-NSP2-1N
CHIKV nsP2 inhibitor
|
RA-NSP2-1N is the negative control of RA-NSP2-1, which is a specific inhibitor of chikungunya virus (CHIKV) nsP2 RNA helicase (nsP2hel). |
| PC-25135 |
RA-NSP2-1
CHIKV nsP2 inhibitor
|
RA-NSP2-1 is a first-in-class, specific inhibitor of chikungunya virus (CHIKV) nsP2 RNA helicase (nsP2hel) with IC50 of 130 nM against unwindase activity of nsP2. |
| PC-24884 |
PRRSV/CD163-IN-1
PRRSV/CD163 inhibitor
|
PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor, effectively inhibits orcine reproductive and respiratory syndrome virus (PRRSV) infection by disrupting the interaction between CD163-SRCR5 and the viral glycoproteins GP2a and GP4, prevents viral attachment and subsequent infection. |
| PC-24294 |
HS83128
HAV inhibitor
|
HS83128 is a potent, hepato-selective inhibitor of hepatitis A virus (HAV), inhibits host cell TENT4A/B terminal nucleotidyltransferases required for efficient HAV RNA synthesis (IC50=6-25 nM), and potent antiviral activity against HAV in cell culture (EC50=0.6 nM). |
| PC-24208 |
TSWV inhibitor Z9
TSWV N protein inhibitor
|
TSWV inhibitor Z9 is a small molecule inhibitor of tomato spotted wilt virus (TSWV) nucleocapsid protein (N), targets N protein (KD=7.6 uM) to inhibit the replication level of the viral ribonucleoprotein (RNP). |
| PC-24207 |
SGC-NSP2PRO-1
CHIKV nsP2 inhibitor
|
SGC-NSP2PRO-1 is a potent, covalent inhibitor of Chikungunya virus (CHIKV) nsP2 cysteine protease (nsP2pro) with IC50 of 40 nM. |
| PC-23811 |
A8-A2
PRRSV NSP11 inhibitor
|
A8-A2 is a specific small molecule inhibitor of PRRSV NSP11 nidoviral uridylate-specific endoribonuclease (NendoU) domain, shows broad-spectrum antiviral avitivity against nidoviruses. |