| Cat. No. |
Product Name |
Information |
| PC-49637 |
H-PGDS inhibitor 1y
H-PGDS inhibitor
|
H-PGDS inhibitor 1y is a potent peripherally restricted H-PGDS inhibitor with IC50 of 9.4 nM, compound 1y is efficacious in four in vivo inflammatory models and exhibits no CNS toxicity. |
| PC-49636 |
H-PGDS inhibitor 8
H-PGDS inhibitor
|
H-PGDS inhibitor 8 is a potent, selective and orally active hematopoietic prostaglandin D synthase (HPGDS) inhibitor with enzyme IC50 of 0.6 nM, and cell IC50 of 32 nM. |
| PC-38689 |
LY3023703
mPGES-1 inhibitor
|
LY3023703 is a potent, highly selective microsomal prostaglandin E synthase 1 (mPGES1) inhibitor, dose-dependently inhibits PGE2 production in human whole blood ex vivo. |
| PC-38642 |
SZ0232
mPGES-2 inhibitor
|
SZ0232 is a small molecule mPGES-2 (microsomal prostaglandin E synthase-2) inhibitor with IC50 of <1 uM, exhibits beneficial effects on modulating β-cell function and glucose metabolism both in vitro and in vivo. |
