| Cat. No. |
Product Name |
Information |
| PC-21170 |
SBE13
PLK1 inhibitor
|
PLK1 inhibitor SBE13 is a potent, selective PLK1 inhibitor with IC50 of 0.2 nM, with little to no inhibition against PLK2/PLK3 (IC50, 65 uM/875 nM). |
| PC-21169 |
Ro3280
PLK1 inhibitor
|
Ro3280 is a potent, specific PLK1 inhibitor with IC50/Kd of 3/0.09 nM, respectively, shows no activity against PLK2/3. |
| PC-21081 |
Allopole
PLK1 PBD inhibitor
|
Allopole is the first allosteric, specfic and cell-permeable inhibitor of the noncatalytic polo-box domain (PBD) of PLK1 (Polo-like kinase 1), Allopole is the prodrug of Allopole-A. |
| PC-20477 |
MCC1019
PLK1 PBD inhibitor
|
MCC1019 is a selective inhibitor of PLK1, targets PLK1 Polo box domain (PBD) with binding IC50 of 16.4 uM, 2.75-fold over PLK2-PBD (IC50=44.1 uM) and > 6-fold higher specificity over PLK3 PBD (IC50 >100 uM). |
