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Request The Product List ofPolo-like Kinase (PLK) Polo-like Kinase (PLK)

Cat. No. Product Name Information
PC-42779

GW843682X

PLK1/3 inhibitor

GW843682X is a potent and selective inhibitor of PLK1 (IC5=2.2 nM) and PLK3 (IC50=9 nM).
PC-23368

TC-S 7005

PLK2 inhibitor

TC-S 7005 is a potent, selective polo-like kinase 2 (PLK2) inhibitor with IC50 of 4 nM, 24 nM and 214 nM for PLK2, PLK3, and PLK1, respectively.
PC-22312

NMS-P937

PLK1 inhibitor

NMS-P937 (Onvansertib, NMS-1286937) is a potent, selective and orally available PLK1 inhibitor with IC50 of 2 nM.
PC-21170

SBE13

PLK1 inhibitor

PLK1 inhibitor SBE13 is a potent, selective PLK1 inhibitor with IC50 of 0.2 nM, with little to no inhibition against PLK2/PLK3 (IC50, 65 uM/875 nM).
PC-21169

Ro3280

PLK1 inhibitor

Ro3280 is a potent, specific PLK1 inhibitor with IC50/Kd of 3/0.09 nM, respectively, shows no activity against PLK2/3.

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