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You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-RUNX1-CBFβ

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Cat. No. Product Name Information
PC-61299

AI-10-104

AI-10-104 is a small molecule inhibitor that interferes with CBFβ binding to RUNX proteins with IC50 of 1.25 uM in FRET assays.
PC-70219

Ro5-3335

Ro5-3335 is a small molecule RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation
PC-45078

AI-10-49

A potent (FRET IC50=260nM) protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1.
PC-61298

RUNX1-IN-17

A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays.
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