| Cat. No. |
Product Name |
Information |
| PC-60210 |
CCG-4986
RGS4 inhibitor
|
CCG-4986 is a on-peptide, selective RGS4 inhibitor that inhibits RGS4/Gα(o) binding with 3 to 5 uM potency. |
| PC-70013 |
CCG-50014
RGS4 inhibitor
|
CCG-50014 (CCG50014) is a potent, selective, covalent inhibitor of RGS4 with IC50 of 30 nM. |
| PC-45956 |
CCG-63808
RGS inhibitor
|
A reversible, allosteric inhibitor of regulator of G-protein signaling (RGS) proteins with a potency order of RGS4 >19=16>8>>7. |
| PC-45955 |
CCG-63802
RGS inhibitor
|
A reversible, allosteric inhibitor of regulator of G-protein signaling (RGS) proteins with a potency order of RGS4 > 19 = 16 > 8 >> 7. |
| PC-23050 |
BMS-192364
RGS agonist
|
BMS-192364 is a small molecule inhibitor of muscarinic G-protein coupled receptor (GPCR) signaling involving G-αq (G-protein alpha subunit), likely acts at the intersection of RGS and G-αq proteins, resulting in the downregulation of GPCR signaling, reduced calcium fluxes, and reduced muscle contraction. |
