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Cat. No. Product Name Information
PC-60401

AX-024 hydrochloride

TCR inhibitor

AX-024 hydrochloride is a potent, orally available inhibitor of TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with IC50 of 1 nM.
PC-60400

AX-024

TCR inhibitor

AX-024 (AX024) is a first-in-class, specific inhibitor of T cell receptor (TCR), specifically inhibits TCR-Nck (SH3.1) interaction and TCR-dependent T cell activation (IC50=1 nM).
PC-60399

AX-000

TCR-Nck inhibitor

AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

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