Cat. No. |
Product Name |
Information |
PC-60401 |
AX-024 hydrochloride
TCR inhibitor
|
AX-024 hydrochloride is a potent, orally available inhibitor of TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with IC50 of 1 nM. |
PC-60400 |
AX-024
TCR inhibitor
|
AX-024 (AX024) is a first-in-class, specific inhibitor of T cell receptor (TCR), specifically inhibits TCR-Nck (SH3.1) interaction and TCR-dependent T cell activation (IC50=1 nM). |
PC-60399 |
AX-000
TCR-Nck inhibitor
|
AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction. |