TOPK (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-35916	SKLB-C05 TOPK inhibitor	SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis.
PC-43047	OTS964 TOPK inhibitor	OTS964 is a dimethylated derivative of OTS514 and potent, selective TOPK inhibitor with IC50 of 28 nM, exhibits excellent in vivo efficacy with liposomal formulation.
PC-70142	ADA-07 TOPK inhibitor	ADA-07 is a novel potent TOPK inhibitor that effectively suppresses SUV-induced activation of MAPKs signal transduction resulting in reduced SUV-induced skin carcinogenesis.
PC-42404	HI-TOPK-032 TOPK inhibitor	HI-TOPK-032 is a novel potent, specific TOPK inhibitor that has no effect on ERK1, JNK1, or p38 kinase activity.
PC-45487	OTS514 PBK/TOPK inhibitor	OTS514 (OTS-514) is a highly potent and selective inhibitor of T-lymphokine-activated killer-cell-originated protein kinase (TOPK, PDZ-binding kinase/PBK) with IC50 of 2.6 nM.

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