| Cat. No. |
Product Name |
Information |
| PC-35916 |
SKLB-C05
TOPK inhibitor
|
SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis. |
| PC-43047 |
OTS-964
TOPK inhibitor
|
OTS-964 is a dimethylated derivative of OTS514 and potent, selective TOPK inhibitor with IC50 of 28 nM, exhibits excellent in vivo efficacy with liposomal formulation. |
| PC-70142 |
ADA-07
TOPK inhibitor
|
ADA-07 is a novel potent TOPK inhibitor that effectively suppresses SUV-induced activation of MAPKs signal transduction resulting in reduced SUV-induced skin carcinogenesis. |
| PC-42404 |
HI-TOPK-032
TOPK inhibitor
|
HI-TOPK-032 is a novel potent, specific TOPK inhibitor that has no effect on ERK1, JNK1, or p38 kinase activity. |
| PC-45487 |
OTS-514
TOPK inhibitor
|
OTS-514 (OTS514) is a highly potent and selective TOPK inhibitor with IC50 of 2.6 nM. |
