| Cat. No. |
Product Name |
Information |
| PC-45460 |
Conivaptan hydrochloride
Vasopressin Receptor inhibitor
|
Conivaptan (YM-087) is a potent, selective nonpeptide vasopressin V1A and V2 receptor antagonist with Ki of 0.48 nM and 3.04 nM respectively. |
| PC-45125 |
Tolvaptan
V2R antagonist
|
Tolvaptan (OPC-41061) is a highly potent selective, competitive vasopressin V2-receptor antagonist with Ki of 0.43 nM, >200-fold more selective than for V1A-receptors. |
| PC-23097 |
Invopressin
V1a receptor agonist
|
Invopressin (OCE-205) is a highly selective Vasopressin V1a receptor (V1a receptor) partial agonist (EC50=1.0 nM) with potential for portal hypertension (PHT). |
| PC-21617 |
PF-184563
V1a receptor antagonist
|
PF-184563 is a potent and selective vasopressin V1a antagonist with IC50 of 6.7 nM (hV1a). |
| PC-21616 |
Relcovaptan
V1a receptor antagonist
|
SR 49059 (SR-49059) is a potent, selective and orally active vasopressin V1a antagonist with Ki of 1.4 nM. |
| PC-21615 |
SRX-246
V1a receptor antagonist
|
SRX-246 (SRX246) is a potent, selective and CNS penetrant human V1a receptor antagonist with Ki of 0.3 nM. |
| PC-21614 |
RGH-122
V1a receptor antagonist
|
RGH-122 is a potent, selective, and orally bioavailable V1a receptor antagonist with Ki/IC50 of 0.3/0.9 nM (hV1a) respectively, >100-fold selectiive over V2 receptor. |
| PC-21436 |
SR-49059
V1AR antagonist
|
SR49059 (SR-49059) is a potent, selective and orally active vasopressin V1a antagonist with Ki of 1.4 nM. |
