| Cat. No. |
Product Name |
Information |
| PC-23254 |
Efaroxan hydrochloride
α2AR antagonist, I1R antagonist
|
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor (α2AR) antagonist, also is a selective I1 imidazoline receptor (I1R)antagonist. |
| PC-23250 |
Clonidine hydrochloride
α2AR agonist
|
Clonidine hydrochloride is a potent alpha 2-adrenergic receptor (α2AR) agonist with Ki of 3.8 nM, also binds to I1 imidazoline receptor (I1R) with Ki of 14.1 nM, a centrally acting antihypertensive agent. |
| PC-23249 |
Clonidine
α2AR agonist
|
Clonidine is a potent alpha 2-adrenergic receptor (α2AR) agonist with Ki of 3.8 nM, also binds to I1 imidazoline receptor (I1R) with Ki of 14.1 nM, a centrally acting antihypertensive agent. |
| PC-23223 |
Apraclonidine hydrochloride
α2 adrenoceptor agonist
|
Apraclonidine hydrochloride (Aplonidine, ALO 2145, ) is a potent and selective alpha2-adrenergic receptor agonist, has the ability to elevate the eye lid, also has been used as a diagnostic test in Horner's syndrome. |
| PC-22867 |
AGN-762
α2B/α2C adrenergic receptor activator
|
AGN-762 is a selective activator of α2B- and α2C-adrenergic receptor subtypes, but not the α2A subtype. |
| PC-22600 |
WB4101
α1A adrenoceptor antagonist
|
WB4101 is a potent, α1A-adrenergic selective antagonist with pKB value of 8.9 in rabbit aorta. |
| PC-22446 |
ATR-127
β2/β3-adrenoceptor agonist
|
ATR-127 is a highly effective β2- and β3-adrenoceptors (ARs) agonist with pEC50 of 6.53 and 5.5 for rat β2-AR and mouse β3-AR, respectively. |
| PC-22239 |
SR59230A
β3AR antagonist
|
SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50 of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. |
| PC-21223 |
ZD7114
beta-adrenoceptor agonist
|
ZD7114 (ICI D7114) is a potent, selective beta-adrenoceptor agonist, selectively stimulates brown fat and increases whole-body oxygen consumption. |
| PC-21196 |
Mirabegron
β3-adrenoceptor agonist
|
Mirabegron (YM178) is a potent, selective selective β3-adrenoceptor agonist with EC50 of 22.4 nM. |
| PC-20987 |
Difluorophenyl Quinazoline
β2AR modulator
|
Difluorophenyl Quinazoline (DFPQ, AP-06-202) is a selective, biased, negative allosteric modulator of β-arrestin recruitment to the β2AR, without effect on on β2AR coupling to Gs. |
| PC-20986 |
L-771688
α1A adrenoceptor antagonist
|
L-771688 (L-771,688, SNAP 6383) is a potent and selective alpha1A (α1A)-adrenoceptor antagonist with binding Ki of 0.13 nM to α1-adrenoceptors in human prostate tissue. |
