| Cat. No. |
Product Name |
Information |
| PC-60507 |
Atabecestat
BACE inhibitor
|
Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease. |
| PC-60085 |
CNP-520
BACE1 inhibitor
|
Umibecestat (CNP520) is a potent, selective, and efficacious β-Secretase (BACE1) inhibitor with IC50 of 11 nM and 30 nM for BACE1 and BACE2, respectively. |
| PC-60084 |
Elenbecestat
BACE1 inhibitor
|
Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease. |
| PC-60045 |
Lanabecestat
BACE1 inhibitor
|
Lanabecestat (AZD-3293, LY-3314814) is a potent, orally active and brain-permeable BACE1 inhibitor with Ki of 0.4 nM. |
| PC-45073 |
Verubecestat
BACE inhibitor
|
Verubecestat (MK-8931) is a potent, selective, structurally unique BACE inhibitor with Ki of 2.2 nM and 0.38 nM for BACE1 and BACE2, respectively. |
| PC-42607 |
LY2811376
BACE1 inhibitor
|
LY2811376 is potent, orally available non-peptidic β-secretase (BACE1) inhibitor with IC50 of 239 nM in enzyme assays. |
