| Cat. No. |
Product Name |
Information |
| PC-22440 |
I1421
CFTR potentiator
|
I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM. |
| PC-22024 |
FDL169
CFTR corrector
|
FDL169 (FDL-169) is a novel F508del-CFTR corrector, restores the function of the defective CFTR protein. |
| PC-22023 |
Posenacaftor sodium
CFTR corrector
|
Posenacaftor (PTI-801) sodium is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate). |
| PC-22022 |
Posenacaftor
CFTR corrector
|
Posenacaftor (PTI-801) is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate). |
| PC-21956 |
CFTR(inh)-172
CFTR inhibitor
|
CFTR(inh)-172 is a potent and selective blocker/inhibitor of CFTR chloride channel with Ki of 200 nM, reversibly inhibits CFTR short-circuit currents. |
| PC-43327 |
Ivacaftor hydrate
|
Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM. |
| PC-43326 |
Ivacaftor benzenesulfonate
|
Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM. |
