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Cat. No. Product Name Information
PC-22440

I1421

CFTR potentiator

I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM.
PC-22024

FDL169

CFTR corrector

FDL169 (FDL-169) is a novel F508del-CFTR corrector, restores the function of the defective CFTR protein.
PC-22023

Posenacaftor sodium

CFTR corrector

Posenacaftor (PTI-801) sodium is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate).
PC-22022

Posenacaftor

CFTR corrector

Posenacaftor (PTI-801) is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate).
PC-21956

CFTR(inh)-172

CFTR inhibitor

CFTR(inh)-172 is a potent and selective blocker/inhibitor of CFTR chloride channel with Ki of 200 nM, reversibly inhibits CFTR short-circuit currents.
PC-43327

Ivacaftor hydrate

Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM.
PC-43326

Ivacaftor benzenesulfonate

Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM.

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