Cat. No. |
Product Name |
Information |
PC-22192 |
Naproxen
COX inhibitor
|
Naproxen is a small molecule anti-inflammatory agent and cyclooxygenase (COX) inhibitor with IC50 of 8.72 and 5.15 μM for COX-1 and COX-2, respectively in cell assay. |
PC-22190 |
Ibuprofen
COX-1 inhibitor
|
Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective cyclooxygenase-1 (COX-1) inhibitor with IC50 value of 13 μM, inhibits cell proliferation, angiogenesis, and induces cell apoptosis, is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. |
PC-21896 |
Celecoxib
COX-2 inhibitor
|
Celecoxib (SC 58635) is a potent selective inhibitor of COX-2 with IC50 of 40 nM, non-steroidal anti-inflammatory drug (NSAID). |
PC-20874 |
Valdecoxib
COX-2 inhibitor
|
Valdecoxib (SC 65872) is a potent and selective inhibitor of COX-2 with IC50 of 5 nM, shows no activity against COX-1. |
PC-20873 |
Etoricoxib
COX-2 inhibitor
|
Etoricoxib (MK-0663) is a potent, selective and orally active inhibitor of COX-2 with IC50 of 1.1 uM for COX-2 (LPS-induced prostaglandin E2 synthesis), shows no activity against COX-1. |
PC-45291 |
Parecoxib sodium
|
A potent and selective COX-2 inhibitor. |