| Cat. No. |
Product Name |
Information |
| PC-38251 |
TM-N1324
GPR39 agonist
|
GPR39 agonist Cpd1324 (TM-N1324) is a potent, selective, orally active GPR39 agonist, activats human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. |
| PC-62256 |
GPR39 agonist 7
GPR39 agonist, Hedgehog inhibitor
|
GPR39 agonist 7 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=20 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels. |
| PC-62255 |
GPR39 agonist 3
GPR39 agonist, Hedgehog inhibitor
|
GPR39 agonist 3 is a Hedgehog pathway inhibitor that has high cellular potency (EC50=5 nM) in the reporter gene assay, activates the orphan receptor GPR39 and potently reduces of Gli1 and Ptch1 mRNA levels. |
| PC-60593 |
TC-G 1008
GPR39 agonist
|
TC-G 1008 (TC-G-1008, GPR39-C3) is a potent, selective, orally bioavailable GPR39 agonist with EC50 of 0.4 and 0.8 nM for rat and human GPR39, respectively. |
| PC-23364 |
Z1780628919
GPR39 antagonist
|
Z1780628919 is a small molecule ligand and antagonist of GRP39, inhibits TC-G-1008-induced inflammatory effects in HUVECs, significantly attenuates Ang II-induced hypertension in mice. |
