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Cat. No. Product Name Information
PC-49656

AVN-944

IMPDH inhibitor

AVN-944 (VX-944) is a potent, selective, noncompetitive inhibitor of both human inosine 5-monophosphate dehydrogenase (IMPDH) isoforms (Ki=6-10 nM).
PC-49653

FF-10501

IMPDH inhibitor

FF-10501 (SM-108, Bredinin aglycone) is a small molecule inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), maintained cell growth inhibitory activities in the azacitidine-resistant cell lines.
PC-35012

VX-148

IMPDH inhibitor

VX-148 (VX148) is a potent, uncompetitive, orally bioavailable IMPDH inhibitor with Ki of 6 nM against IMPDH type II enzyme.
PC-35011

Merimepodib

IMPDH inhibitor

Merimepodib (VX-497, VI-21497, MMPD) is a potent, selective, reversible, uncompetitive IMPDH inhibitor with broad-spectrum antiviral activity.
PC-61690

FF-10501-01

IMPDH inhibitor

FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.
PC-70216

Sappanone A

IMPDH2 inhibitor

Sappanone A is a homoisoflavanone found in Caesalpinia sappan, a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with Kd of 3.944 nM, almost 10 times lower than the Kd of binding to IMPDH1.
PC-70215

IMPDH2-IN-5

IMPDH2 inhibitor

IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).

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