| Cat. No. |
Product Name |
Information |
| PC-23681 |
1ACTA
IRE1α S-nitrosylation inhibitor
|
1ACTA is a specific small molecule inhibitor of IRE1α S-nitrosylation, selectively prevents the NO-induced reduction of RNase activity. |
| PC-23415 |
IXA4
IRE1/XBP1s activator
|
IXA4 is a specific activator of IRE1/XBP1s signalling activator, promotes IRE1-dependent XBP1 splicing, selective activates the IRE1/XBP1s signaling. |
| PC-22296 |
IRE1α inhibitor 16
IRE1α inhibitor
|
IRE1α inhibitor 18 is a potent, selective and allosteric inhibitor of IRE1α endonuclease activity with enzyme IC50 of 13 nM, cellular IRE1α IC50 of 99 nM in XBP1-Luc cellular assays. |
| PC-22293 |
G-5758
IRE1α inhibitor
|
G-5758 (G5758) is a potent and selective, orally active IRE1α inhibitor with IC50 of 0.27 nM in HTRF IRE1α binding assays, inhibits IRE1α-Rnase with IC50 of 4.3 nM. |