Cat. No. |
Product Name |
Information |
PC-36042 |
MLT-748
MALT1 inhibitor
|
MLT-748 (MLT748) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 5 nM, does not show inhibitory activity against 22 other tested human proteases (IC50>100 uM). |
PC-35426 |
MALT1 paracaspase inhibitor 3
MALT1 inhibitor
|
MALT1 paracaspase inhibitor 3 is a potent, specific, covalent inhibitor of MALT1 paracaspase with Ki of 10 nM, exhibits 10-and 100-fold improved potency in vitro and in vivo compared with Z-VRPR-fmk. |
PC-42938 |
MALT1 inhibitor MI-2
MALT1 inhibitor
|
MALT1 inhibitor MI-2 is a selective, irreversible MALT1 paracaspase inhibitor with IC50 of 5.84 uM, displays little activity against the related caspase family members caspase-3, -8, and -9. |
PC-25076 |
Ocipumaltib
MALT1 inhibitor
|
Ocipumaltib is a potent, selective MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) inhibitor, potently inhibits human MALT1 by 99% at 3 uM. |
PC-22030 |
ABBV-MALT1
MALT1 inhibitor
|
ABBV-MALT1 is a potent, selective, allosteric inhibitor of the MALT1 paracaspase with binding KD of 37 nM, exhibits potent biochemical inhibition of MALT1 protease activity with IC50 of 349 nM. |