| Cat. No. |
Product Name |
Information |
| PC-73444 |
Safimaltib
MALT1 inhibitor
|
Safimaltib (JNJ-67856633) is a potent, selective, allosteric inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) protease activity. |
| PC-36043 |
MLT-747
MALT1 inhibitor
|
MLT-747 (MLT747) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 14 nM. |
| PC-36042 |
MLT-748
MALT1 inhibitor
|
MLT-748 (MLT748) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 5 nM, does not show inhibitory activity against 22 other tested human proteases (IC50>100 uM). |
| PC-35426 |
MALT1 paracaspase inhibitor 3
MALT1 inhibitor
|
MALT1 paracaspase inhibitor 3 is a potent, specific, covalent inhibitor of MALT1 paracaspase with Ki of 10 nM, exhibits 10-and 100-fold improved potency in vitro and in vivo compared with Z-VRPR-fmk. |
| PC-42938 |
MALT1 inhibitor MI-2
MALT1 inhibitor
|
MALT1 inhibitor MI-2 is a selective, irreversible MALT1 paracaspase inhibitor with IC50 of 5.84 uM, displays little activity against the related caspase family members caspase-3, -8, and -9. |
| PC-25812 |
(S)-mepazine
MALT1 inhibitor
|
(S)-mepazine is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.26 uM, has approximately 10-fold greater MALT1 inhibitory activity than (R)-mepazine. |
| PC-25811 |
Mepazine
MALT1 inhibitor
|
Mepazine (Pecazine) is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.83 uM. |
| PC-25810 |
MPT-0118
MALT1 inhibitor
|
MPT-0118 ((S)-mepazine succinate) is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.26 uM, has approximately 10-fold greater MALT1 inhibitory activity than (R)-mepazine. |
| PC-25809 |
SGR-1505
MALT1 inhibitor
|
SGR-1505 (SGR1505) is a highly potent, allosteric MALT1 (paracaspase 1, PCASP1) inhibitor with biochemical IC50 of 1.3 nM. |
