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Cat. No. Product Name Information
PC-42035

eFT508

MNK1/2 inhibitor

eFT508 (Tomivosertib) is a potent, highly selective, reversible, ATP-competitive, and orally bioavailable MNK1 and MNK2 inhibitor with IC50 of 1-2 nM in enzyme assays.
PC-42633

CGP57380

MNK1 inhibitor

CGP57380 (CGP-57380) is a cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM.
PC-45112

Cercosporamide

MNK inhibitor

Cercosporamide is a broad-spectrum natural antifungal compound that acts as a selective and highly potent fungal Pkc1 kinase inhibitor, also inhibits Mnk inhibitor with IC50 of 116 nM and 11 nM for Mnk1 and Mnk2, respectively.
PC-24273

MNK inhibitor EB1

MNK inhibitor

MNK inhibitor EB1 is potent inhibitor of inhibitor of MNK with IC50 of 0.69 uM (MNK1) and 9.4 uM (MNK2), most likely binds to the allosteric binding side adjacent to the ATP binding pocket.
PC-24272

NUCC-0200808

MNK inhibitor

NUCC-0200808 is a potent selective, orally bioavailable inhibitor of mitogen-activated protein kinase (MAPK) interacting kinase MNK1 and MNK2 with IC50 of 42 nM and 29 nM, respectively.

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