Mitochondrial Permeability Transition Pore (mPTP) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-62135	ML404 mPTP inhibitor	ML404 is a small molecule inhibitor of mitochondrial permeability transition pore (mtPTP, mPTP), inhibits mitochondrial swelling with EC50 of 4.9 nM, shows no effect on mitochondrial coupling at >100 uM.
PC-62134	Olesoxime mPTP inhibitor	Olesoxime (TRO 19622) is a cholesterol-like compound that binds directly to two components of the mitochondrial permeability transition pore (mPTP): the voltage-dependent anion channel and TSPO (or PBR).
PC-62133	TRO 40303 mPTP inhibitor	TRO 40303 is a novel cardioprotective compound that delays mitochondrial permeability transition pore (mPTP) opening, binds specifically to TSPO at the cholesterol site (Ki=150 nM).
PC-62132	ER-000444793 mPTP inhibitor	ER-000444793 is a potent, cyclophilin D-independent inhibitor of mitochondrial permeability transition pore (mPTP) with with IC50 of 2.8 uM.
PC-62131	GNX-865 mPTP inhibitor	GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling).
PC-60363	DS44170716 MPT inhibitor	DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria.

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