| Cat. No. |
Product Name |
Information |
| PC-62135 |
ML404
mPTP inhibitor
|
ML404 is a small molecule inhibitor of mitochondrial permeability transition pore (mtPTP, mPTP), inhibits mitochondrial swelling with EC50 of 4.9 nM, shows no effect on mitochondrial coupling at >100 uM. |
| PC-62134 |
Olesoxime
mPTP inhibitor
|
Olesoxime (TRO 19622) is a cholesterol-like compound that binds directly to two components of the mitochondrial permeability transition pore (mPTP): the voltage-dependent anion channel and TSPO (or PBR). |
| PC-62133 |
TRO 40303
mPTP inhibitor
|
TRO 40303 is a novel cardioprotective compound that delays mitochondrial permeability transition pore (mPTP) opening, binds specifically to TSPO at the cholesterol site (Ki=150 nM). |
| PC-62132 |
ER-000444793
mPTP inhibitor
|
ER-000444793 is a potent, cyclophilin D-independent inhibitor of mitochondrial permeability transition pore (mPTP) with with IC50 of 2.8 uM. |
| PC-62131 |
GNX-865
mPTP inhibitor
|
GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling). |
| PC-60363 |
DS44170716
MPT inhibitor
|
DS44170716 is a small molecule MPT (mitochondrial permeability transition) inhibitor of that inhibits Ca2+-induced MPT in rat liver isolated mitochondria. |
