| Cat. No. |
Product Name |
Information |
| PC-42261 |
SR12813
PXR agonist
|
SR12813 (GW485801) is potent and efficacious pregnane X receptor (PXR) activator with EC50 of 200 and 700 nM for human and rabbit PXR, respectively. |
| PC-21198 |
SJPYT-318
PXR agonist
|
SJPYT-318 is a highly selective pregnane X receptor (PXR) agonist, targets PXR ligand-binding domain (LBD), exhibits selectivity for PXR LBD over LXR LBDs for recruiting SRC-1. |
| PC-38840 |
FKK6
hPXR agonist
|
FKK6 (Felix Kopp Kortagere 6) is a specific human pregnane X receptor (hPXR) agonist with IC50 of 1.56 uM in a cell‐free competitive hPXR TR‐FRET‐binding assays. |
| PC-62524 |
SJB7
|
SJB7 is a close analog of SPA70 and hPXR agonist, interacts with the ligand-binding domain (LBD) of hPXR.. |
| PC-62523 |
SPA70
|
SPA70 is a potent and selective hPXR antagonist (IC50=0.51 uM) that interacts with the ligand-binding domain (LBD) of hPXR, inhibits hPXR in human hepatocytes and mouse models and enhances the chemosensitivity of cancer cells. |
| PC-60008 |
C2BA-4
|
A potent, specific human Pregnane X receptor (hPXR) activator with EC50 of 49 nM. |
