| Cat. No. |
Product Name |
Information |
| PC-22006 |
CYT-0851
RAD51 inhibitor
|
CYT-0851 (Emzadirib) is a potent, selective and oral inhibitor of RAD51-mediated DNA repair, inhibits homologous recombination (HR) leading to an accumulation of unrepaired DSBs and tumor cell death. |
| PC-38266 |
CAM833
RAD51-BRCA2 inhibitor
|
CAM833 (CAM-833) is a potent, specific chemical inhibitor of the RAD51-BRCA2 interaction and RAD51 oligomerization with Kd of 366 nM. |
| PC-62842 |
RAD51 inhibitor B02
RAD51 inhibitor
|
RAD51 inhibitor B02 is a small molecule that specifically inhibits the DNA strand exchange activity of human RAD51 with IC50 of 27.4 uM, disrupts RAD51 binding to DNA, inhibits HR and increases cell sensitivity to DNA damage. |
| PC-61230 |
DIDS
RAD51 inhibitor
|
DIDS is a small molecule inhibitor of RAD51-mediated homologous recombination. |
| PC-45715 |
RS-1
RAD51 activator
|
RS-1 is a homology-directed repair (HDR) enhancer and RAD51 activator, enhances HDR 3- to 6-fold depending on the locus and transfection method. |
| PC-45083 |
RI-2
RAD51 inhibitor
|
RI-2 (RAD51 inhibitor 2) is a reversible RAD51 inhibitor with IC50 of 44 uM in the standard DNA binding assays. |
| PC-44335 |
RI-1
RAD51 inhibitor
|
RI-1 (RAD51 Inhibitor 1) is a cell-permeable RAD51 inhibitor with IC50 of 5-30 uM range. |
