| Cat. No. |
Product Name |
Information |
| PC-26232 |
RORγ inhibitor Cpd 21
RORγ inhibitor
|
RORγ inhibitor Cpd 21 is potent, selective RORγ inhibitor with EC50 of 84 nM (hRORγ). |
| PC-24369 |
SR1078
RORα/γ agonist
|
SR1078 a selective synthetic RORα/RORγ agonist / ligand, directly binds to the ligand binding domain of RORα and RORγ, increases the transcriptional activity. |
| PC-22403 |
GNE-0946
RORγ inverse agonist
|
GNE-0946 is a potent and selective RORc (RORγ) inverse agonist with cell EC50 of 4 nM, inhibits IL-17 production in hPBMC with EC50 of 17 nM. |
| PC-21716 |
W6134
RORγ inhibitor
|
W6134 (RORγ covalent inhibitor 29) is a first-in-class, potent and selective RORγ covalent inhibitor with IC50 of 0.21 uM, targets the Cys320 of RORγ. |