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Cat. No. Product Name Information
PC-22403

GNE-0946

RORγ inverse agonist

 GNE-0946 is a potent and selective RORc (RORγ) inverse agonist with cell EC50 of 4 nM, inhibits IL-17 production in hPBMC with EC50 of 17 nM.
PC-21716

W6134

RORγ inhibitor

 W6134 (RORγ covalent inhibitor 29) is a first-in-class, potent and selective RORγ covalent inhibitor with IC50 of 0.21 uM, targets the Cys320 of RORγ.
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