| Cat. No. |
Product Name |
Information |
| PC-21707 |
RIPK1 inhibitor 62
RIPK1 inhibitor
|
RIPK1 inhibitor 62 is a potent, selective, orally bioavailable type-II kinase inhibitor of RIPK1 with IC50 of 3.5 nM (hRIPK1), 200-fold less potent against hRIPK3. |
| PC-21572 |
AC-003
RIPK1 inhibitor
|
AC-003 is a novel oral small-molecule inhibitor of receptor interacting protein kinase 1(RIPK1) and has the potential for treating idiopathic pulmonary fibrosis. |
| PC-20562 |
aYM155
YM155 prodrug
|
aYM155 is a brain-penetrating prodrug form of YM155 (Cat. PC-42439, potent survivin inhibitor), displays potent cell killing activity against a broad panel of patient-derived GBM cancer stem-like cells (IC50=0.7-10 nM). |