| Cat. No. |
Product Name |
Information |
| PC-62633 |
RIPK1 inhibitor 22
RIPK1 inhibitor
|
RIPK1 inhibitor 22 is a highly potent, orally available, and brain-penetrating RIP1 kinase (RIPK1) inhibitor with pKi of 9.04. |
| PC-60549 |
GSK963
RIPK1 inhibitor
|
GSK-963 (GSK963) is a potent and selective inhibitor of RIP1 kinase (RIPK1) with IC50 of 29 nM in FP binding assays. |
| PC-70204 |
Sibiriline
RIPK1 inhibitor
|
Sibiriline is a specific competitive RIPK1 inhibitor with IC50 of 1.03 uM, 100-fold less potent for RIPK3. |
| PC-60160 |
RIPK2 inhibitor 8
RIPK2 inhibitor
|
RIPK2 inhibitor 8 (RIPK2-IN-4) is a potent, selective, orally available RIPK2 inhibitor with IC50 of 3 nM. |
| PC-42439 |
YM-155
Survivin inhibitor, RIPK2 inhibitor
|
Sepantronium bromide (YM-155) is a potent, specific survivin inhibitor that inhibits survivin promoter activity with IC50 of 0.54 nM, targets RIPK2 kinase activity. |
| PC-45707 |
RIPK2 inhibitor 2
RIPK2 inhibitor
|
RIPK2 inhibitor 2 (RIPK2-IN-2) is a potent, selective receptor interacting protein-2 (RIP2) kinase inhibitor. |
| PC-42102 |
GSK583
RIPK2 inhibitor
|
GSK583 is a potent, selective and orally bioavailable RIPK2 kinase inhibitor with IC50 of 5 nM and 2 nM for human and rat RIP2, respectively. |
| PC-45564 |
WEHI-345
RIPK2 inhibitor
|
WEHI-345 is a potent and selective RIPK2 inhibitor with IC50/Kd of 130/46 nM. |
| PC-42301 |
RIPA-56
RIPK1 inhibitor
|
RIPA-56 is a highly potent, selective, stable Receptor-interacting protein kinase 1 (RIPK1, RIP1) inhibitor with IC50 of 13 nM. |
| PC-42065 |
GSK-481
RIPK1 inhibitor
|
GSK-481 (GSK481) is a highly potent, monokinase selective and ATP-competitive inhibitor of RIP1 kinase (RIPK1) with biochemical IC50 of 10 nM. |
| PC-26020 |
WJH-C19
RIPK1 inhibitor
|
WJH-C19 is a novel potent, selective RIPK1 inhibitor with IC50 of 5.7 nM, shows negligible PI3Kα and RIPK2/3. |
| PC-25543 |
RIPK1 inhibitor 3-47
RIPK1 inhibitor
|
RIPK1 inhibitor 3-47 is a specific, allosteric small molecule inhibitor of RIPK1, effectively reduces phosphorylation of RIPK1 at 12 nM in WB assays (human NP cells), protects viability of TNF-α-treated NP cells. |
