| Cat. No. |
Product Name |
Information |
| PC-20360 |
Febuxostat
Xanthine oxidase inhibitor
|
Febuxostat (TEI-6720) is a potent xanthine oxidase/xanthine dehydrogenase (XO) inhibitor, inhibit bovine milk XO, and mouse liver and rat liver XO with IC50 of 1.4, 1.8 and 2.2 nM, respectively. |
| PC-20359 |
Niraxostat
Xanthine oxidase inhibitor
|
Niraxostat (Y-700) is a potent, long-lasting, orally effective xanthine oxidase (XO) inhibitor with IC50 of 5.8 nM, exhibits potent and long-lasting hypouricemic effect in rat model of hyperuricemia. |
| PC-20358 |
Topiroxostat
XOR inhibitor
|
Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM. |
| PC-38682 |
Tigulixostat
XAO inhibitor
|
Tigulixostat (LC350189) is a novel selective xanthine oxidase (XAO) inhibitor under clinical development for the management of hyperuricemia. |
| PC-47187 |
Benzbromarone
TMEM16A inhibitor
|
Benzbromarone (NSC 85433, MJ10061) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=8.3 uM, EYA3), exhibits selectivity for EYA over PTP1B. |
| PC-22859 |
CC15009
XOR inhibitor
|
CC15009 is a potent, specific xanthine oxidoreductase (XOR) inhibitor, inhibits XOR-catalyzed uric acid synthesis in vitro with IC50 of 0.237 nM. |
