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Cat. No. Product Name Information
PC-49073

VP15 hydrochloride

AChE inhibitor

VP15 hydrochloride (VP-15 HCl) is a BBB-penetrant, orally active, multitarget directed ligand against acetylcholine and monoamine oxidase enzymes with IC50 of 0.04 and 0.37 uM for AChE and MAO-B, respectively, >600-fold selectivity over BuChE.
PC-63361

Zanapezil

AChE inhibitor

Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM.
PC-62461

Ipidacrine

AChE inhibitor

Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.
PC-62460

Ipidacrine hydrochloride

AChE inhibitor

Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.
PC-61035

TAK-802

AChE inhibitor

TAK-802 is potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM.
PC-22544

UW-MD-95

BChE inhibitor

UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD.
PC-22297

S21-1011

BChE inhibitor

S21-1011 is a potent, selective, BBB-penetrant butyrylcholinesterase (BChE) inhibitor with IC50 of 59 nM and 162 nM for eqBChE and hBChE, respectively.
PC-61036

TAK-802 hydrochloride

A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM.
PC-60067

AD-35 hydrochloride

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.
PC-60066

AD-35

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.
PC-60065

AD-35 phosphate

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.
PC-42789

Rivastigmine tartrate

An acetylcholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.

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