| Cat. No. |
Product Name |
Information |
| PC-45333 |
Aldicarb sulfone
Insecticide
|
Aldicarb sulfone is a arbamate insecticide that acts as a fast-acting cholinesterase inhibitor. |
| PC-45332 |
Aldicarb
Cholinesterase inhibitor
|
Aldicarb is a carbamate insecticide that acts as a fast-acting cholinesterase inhibitor. |
| PC-27446 |
ROS151
AChE inhibitor
|
ROS151 is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 14 nM (hAChE), as well as a chelator of Fe3+ and Cu2+, shows weak activity against eqBChE, hFAAH, hMAO-A and hMAO-B. |
| PC-27408 |
Donepezil hydrochloride
AChE inhibitor
|
Donepezil hydrochloride (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. |
| PC-27407 |
Anivecrine succinate
AChE inhibitor
|
Anivecrine succinate (Octohydroaminoacridine succinate) is a tacrine analogue and acetylcholinesterase (AChE) inhibitor, potentially inhibits both AChE and butyrylcholinesterase (BuChE), ignificantly improves cognitive function and behaviour in Alzheimer's disease (AD). |
| PC-27406 |
Anivecrine
AChE inhibitor
|
Anivecrine (Octohydroaminoacridine) is a tacrine analogue and acetylcholinesterase (AChE) inhibitor, potentially inhibits both AChE and butyrylcholinesterase (BuChE), ignificantly improves cognitive function and behaviour in Alzheimer's disease (AD). |
| PC-26807 |
Bisnorcymserine
BChE inhibitor
|
Bisnorcymserine ((-)-Bisnorcymserine) is a potent inhibitor for butyrylcholinesterase (BChE) with IC50 of 0.228 nM, reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates AD in elderly rat models. |
| PC-26290 |
DL0410
AChE/BuChE inhibitor, H3R antagonist
|
DL0410 is a synthetic dual acetylcholinesterase (AChE)/butyrocholinesterase (BuChE) inhibitor with IC50 of 0.286/3.96 uM, also inhibit histamine receptor 3 (H3R) with IC50 of 0.308 uM, shows neuroprotective effects both in vitro and in vivo. |
| PC-26234 |
MR2938
AChE inhibitor
|
MR2938 is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 5.04 uM, suppresses NO production in RAW 264.7 cells with IC50 of 3.29 uM. |
| PC-24702 |
BChE inhibitor (R)-(-)-3
BChE inhibitor
|
BChE inhibitor (R)-(-)-3 is a potent, selective butyrylcholinesterase (BChE) inhibitor with Ki of 6.6 nM, IC50 of 12 nM (hBChE), >1500-fold selective over hAChE. |
| PC-22544 |
UW-MD-95
BChE inhibitor
|
UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD. |
| PC-22297 |
S21-1011
BChE inhibitor
|
S21-1011 is a potent, selective, BBB-penetrant butyrylcholinesterase (BChE) inhibitor with IC50 of 59 nM and 162 nM for eqBChE and hBChE, respectively. |
