Aldose Reductase (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofAldose Reductase Aldose Reductase

Cat. No.	Product Name	Information
PC-45580	Caficrestat Aldose reductase inhibitor	AT-001 (Caficrestat) is a highly potent, selective inhibitor of aldose reductase enzymatic activity with IC50 of 28.9 pM.
PC-45922	Epalrestat Aldose reductase inhibitor	Epalrestat (ONO-2235) is a noncompetitive and reversible aldose reductase inhibitor with IC50 of 10 nM and 26 nM for purified aldose reductase from rat lens and human placenta, respectively.
PC-28414	AKR1C3-IN-1 AKR1C3 inhibitor	AKR1C3-IN-1 is a highly potent, selective inhibitor of AKR1C3 with IC50 of 13 nM.
PC-28397	Isoliquiritigenin Aldose Reductase inhibitor	Isoliquiritigenin is a natural flavonoid that exhibits anti-inflammatory, anti-tumor and antioxidant activities, inhibits aldose reductase with an IC50 of 320 nM, is also a potent inhibitor of influenza virus replication with EC50 of 24.7 uM, also targets METTL3 with anti-leukemic effect.
PC-24205	S07-2010 AKR1C inhibitor	S07-2010 is a potent, pan aldo-keto reductase 1C3 (AKR1C3) inhibitor with IC50 of 0.19, 0.36, 0.47, and 0.73 uM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively.

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