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Cat. No. Product Name Information
PC-23116

pyrone-211

AKR1C3 inhibitor, GPR84 agonist

pyrone-211 is a potent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), also is a potent agonist of the semi-orphan receptor GPR84.
PC-22474

WJ-39

Aldose reductase inhibitor

WJ-39 (Darirestat potassium salt) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
PC-22473

Darirestat

Aldose reductase inhibitor

WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
PC-22254

AKR1C3 inhibitor 1

AKR1C3 inhibitor

AKR1C3 inhibitor 1 is a potent, selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with IC50 of 110 nM, 127-fold selective over AKR1C2.

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