Cat. No. |
Product Name |
Information |
PC-23116 |
pyrone-211
AKR1C3 inhibitor, GPR84 agonist
|
pyrone-211 is a potent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), also is a potent agonist of the semi-orphan receptor GPR84. |
PC-22474 |
WJ-39
Aldose reductase inhibitor
|
WJ-39 (Darirestat potassium salt) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. |
PC-22473 |
Darirestat
Aldose reductase inhibitor
|
WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. |
PC-22254 |
AKR1C3 inhibitor 1
AKR1C3 inhibitor
|
AKR1C3 inhibitor 1 is a potent, selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with IC50 of 110 nM, 127-fold selective over AKR1C2. |