Cat. No. |
Product Name |
Information |
PC-45711 |
(R)-BPO-27
CFTR inhibitor
|
(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance inhibitor with IC50 of 4 nM. |
PC-23052 |
Deutivacaftor
CFTR potentiator
|
Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9) is a potent, orally active CFTR potentiator/modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE. |
PC-22024 |
FDL169
CFTR corrector
|
FDL169 (FDL-169) is a novel F508del-CFTR corrector, restores the function of the defective CFTR protein. |
PC-22023 |
Posenacaftor sodium
CFTR corrector
|
Posenacaftor (PTI-801) sodium is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate). |
PC-22022 |
Posenacaftor
CFTR corrector
|
Posenacaftor (PTI-801) is a newly developed p.Phe508del-CFTR corrector with EC50 of 0.52 uM (HS-YFP quenching rate). |
PC-21956 |
CFTR(inh)-172
CFTR inhibitor
|
CFTR(inh)-172 is a potent and selective blocker/inhibitor of CFTR chloride channel with Ki of 200 nM, reversibly inhibits CFTR short-circuit currents. |
PC-43327 |
Ivacaftor hydrate
|
Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM. |
PC-43326 |
Ivacaftor benzenesulfonate
|
Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM. |