| Cat. No. |
Product Name |
Information |
| PC-38751 |
YK-2-69
DYRK2 inhibitor
|
YK-2-69 is a potent, hilghly selective inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) with IC50 value of 9 nM, shows weak inhibition against DYRK1B (IC50=542 nM) and no activity against DYRK1A/3/4 (IC50>1,000 nM). |
| PC-73293 |
BT173
HIPK2 inhibitor
|
BT173 is a small molecule allosteric inhibitor of HIPK2-Smad3 interaction, specifically inhibits the TGF-β1/Smad3 pathway. |
| PC-42939 |
AZ191
DYRK1B inhibitor
|
AZ191 is a potent, selective DYRK1B inhibitor with IC50 of 17 nM, displays 10-fold selectivity over DYRK1A and no activity against DYRK2 (IC50=1890 nM). |
| PC-42167 |
TBID
HIPK2 inhibitor
|
tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM. |
| PC-21660 |
Y020-3945
DYRK1A inhibitor
|
Y020-3945 is a selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor with IC50 of 0.53 uM. |
| PC-21506 |
Leucettinib-21
CLK/DYRK inhibitor
|
Leucettinib-21 is a potent, selective DYRKs and CLKs kinases with IC50 of 2.4, 6.7, 12, 33, and 5 nM for DYRK1A, DYRK1B, CLK1, CLK2, and CLK4, respectively. |
| PC-21496 |
EHT 1610
DYRK1A inhibitor
|
EHT 1610 is a potent inhibitor of DYRKs family kinases with IC50s of 0.36 nM (DYRK1A), 0.59 nM (DYRK1B), respectively. |
| PC-21495 |
FC162
DYRK1A inhibitor
|
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively. |
| PC-21494 |
EHT 5372
DYRK1A inhibitor
|
EHT 5372 is a highly potent and selective inhibitor of DYRKs family kinases with IC50s of 0.22, 0.28, 10.8, 93.2 nM for DYRK1A, DYRK1B, DYRK2, DYRK3, respectively. |
| PC-21469 |
LDN192960
DYRK2 inhibitor
|
LDN192960 (LDN 192960) is a highly potent and selective DYRK2 inhibitor with IC50 of 13 nM toward DYRK2 at 50 uM ATP. |
| PC-49263 |
AZ Dyrk1B 33
DYRK inhibitor
|
AZ Dyrk1B 33 is a potent dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with IC50 of 16.8/39/254/430 nM for DYRK1A/1B/2/3, respectively, does not inhibit DYRK4 (IC50>30 uM). |
| PC-38492 |
DYRK2 inhibitor C17
DYRK2 inhibitor
|
DYRK2 inhibitor C17 is a potent, selective DYRK2 inhibitor with IC50 of 9 nM, weakly inhibits DYRK3 (IC50=68 nM), and does not inhibit DYRK1A/1B (IC50>2000 nM). |
