| Cat. No. |
Product Name |
Information |
| PC-23234 |
DYR219
DYRK1 inhibitor
|
DYR219 is a potent, selective, type 1 ATP-competitive inhibitor of DYRK1 with IC50 of 34 nM (DYRK1A) and 29 nM (DYRK1B), induces degradation of Dyrk1a protein. |
| PC-23001 |
DYRK inhibitor ID-8
DYRK inhibitor
|
DYRK inhibitor ID-8 is a small molecule dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor, enhances Wnt-induced human embryonic stem cell (hESC) survival and proliferation. |
| PC-22601 |
DYC-1
DYRK2/HDAC8 inhibitor
|
DYC-1 is a potent, dual-target DYRK2/HDAC8 inhibitor with IC50 of 5.27 and 8.06 nM respectively, exhibits potent antiproliferative and antitumor activity against liver cancer. |
| PC-22437 |
proINDY
DYRK1A inhibitor
|
proINDY is the acetylated derivative prodrug of INDY, which is a potent, selective and ATP-competitive inhibitor of Dyrk1A, effectively recovers Xenopus embryos from head malformation induced by Dyrk1A overexpression. |
| PC-22436 |
INDY
DYRK1A inhibitor
|
INDY is a potent, selective and ATP-competitive inhibitor of Dyrk1A withIC50 and Ki values of 0.24 and 0.18 μM, respectively. |
| PC-21660 |
Y020-3945
DYRK1A inhibitor
|
Y020-3945 is a selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor with IC50 of 0.53 uM. |
| PC-21496 |
EHT 1610
DYRK1A inhibitor
|
EHT 1610 is a potent inhibitor of DYRKs family kinases with IC50s of 0.36 nM (DYRK1A), 0.59 nM (DYRK1B), respectively. |
| PC-21495 |
FC162
DYRK1A inhibitor
|
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively. |
| PC-21494 |
EHT 5372
DYRK1A inhibitor
|
EHT 5372 is a highly potent and selective inhibitor of DYRKs family kinases with IC50s of 0.22, 0.28, 10.8, 93.2 nM for DYRK1A, DYRK1B, DYRK2, DYRK3, respectively. |
| PC-73291 |
CVM-6-139-1
HIPK2 inhibitor
|
CVM-6-139-1 (HIPK2 inhibitor A64) is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 401 nM. |
