| Cat. No. |
Product Name |
Information |
| PC-21495 |
FC162
DYRK1A inhibitor
|
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively. |
| PC-21494 |
EHT 5372
DYRK1A inhibitor
|
EHT 5372 is a highly potent and selective inhibitor of DYRKs family kinases with IC50s of 0.22, 0.28, 10.8, 93.2 nM for DYRK1A, DYRK1B, DYRK2, DYRK3, respectively. |
| PC-21469 |
LDN192960
DYRK2 inhibitor
|
LDN192960 (LDN 192960) is a highly potent and selective DYRK2 inhibitor with IC50 of 13 nM toward DYRK2 at 50 uM ATP. |
| PC-49263 |
AZ Dyrk1B 33
DYRK inhibitor
|
AZ Dyrk1B 33 is a potent dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with IC50 of 16.8/39/254/430 nM for DYRK1A/1B/2/3, respectively, does not inhibit DYRK4 (IC50>30 uM). |
| PC-38492 |
DYRK2 inhibitor C17
DYRK2 inhibitor
|
DYRK2 inhibitor C17 is a potent, selective DYRK2 inhibitor with IC50 of 9 nM, weakly inhibits DYRK3 (IC50=68 nM), and does not inhibit DYRK1A/1B (IC50>2000 nM). |
| PC-73294 |
MU1787
HIPK inhibitor
|
MU1787 is a potent, highly selective HIPK inhibitor with IC50 of 285/123/283 nM for HIPK1/2/3, repectively. |
| PC-73292 |
JWD-065
HIPK2 inhibitor
|
JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM. |
| PC-73291 |
CVM-6-139-1
HIPK2 inhibitor
|
CVM-6-139-1 (HIPK2 inhibitor A64) is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 401 nM. |
| PC-73113 |
LDN-192960 hydrochloride
DYRK inhibitor
|
LDN192960 (LDN 192960) is a highly potent and selective DYRK2 inhibitor with IC50 of 13 nM toward DYRK2 at 50 uM ATP. |
| PC-43249 |
Mirk-IN-1
|
Mirk-IN-1 is a potent, specific inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 68 nM and 22 nM respectively, shows SW620 cell IC50 of 1.9 uM. |
