| Cat. No. |
Product Name |
Information |
| PC-73294 |
MU1787
HIPK inhibitor
|
MU1787 is a potent, highly selective HIPK inhibitor with IC50 of 285/123/283 nM for HIPK1/2/3, repectively. |
| PC-73292 |
JWD-065
HIPK2 inhibitor
|
JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM. |
| PC-73291 |
CVM-6-139-1
HIPK2 inhibitor
|
CVM-6-139-1 (HIPK2 inhibitor A64) is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 401 nM. |
| PC-73113 |
LDN-192960 hydrochloride
DYRK inhibitor
|
LDN192960 (LDN 192960) is a highly potent and selective DYRK2 inhibitor with IC50 of 13 nM toward DYRK2 at 50 uM ATP. |
| PC-72351 |
GNF2133
DYRK1A inhibitor
|
GNF2133 (GNF-2133) is a potent and selective DYRK1A inhibitor with IC50 of 6 nM, without inhibitory effect on GSK3β. |
| PC-43249 |
Mirk-IN-1
|
Mirk-IN-1 is a potent, specific inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 68 nM and 22 nM respectively, shows SW620 cell IC50 of 1.9 uM. |
