| Cat. No. |
Product Name |
Information |
| PC-23236 |
DYR530
DYRK1 inhibitor
|
DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A). |
| PC-23235 |
DYR533
DYRK1 inhibitor
|
DYR533 is a potent, selective inhibitor of DYRK1 with Kd of 1.4 nM (DYRK1A), blocks mnb phosphorylation of human Tau expressed in Drosophila neurons. |
| PC-23234 |
DYR219
DYRK1 inhibitor
|
DYR219 is a potent, selective, type 1 ATP-competitive inhibitor of DYRK1 with IC50 of 34 nM (DYRK1A) and 29 nM (DYRK1B), induces degradation of Dyrk1a protein. |
| PC-23001 |
DYRK inhibitor ID-8
DYRK inhibitor
|
DYRK inhibitor ID-8 is a small molecule dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor, enhances Wnt-induced human embryonic stem cell (hESC) survival and proliferation. |
| PC-22747 |
ZJCK-6-46
DYRK1A inhibitor
|
ZJCK-6-46 is a potent, selective, and orally available dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor with IC50 of 0.68 nM. |
| PC-22601 |
DYC-1
DYRK2/HDAC8 inhibitor
|
DYC-1 is a potent, dual-target DYRK2/HDAC8 inhibitor with IC50 of 5.27 and 8.06 nM respectively, exhibits potent antiproliferative and antitumor activity against liver cancer. |
| PC-22437 |
proINDY
DYRK1A inhibitor
|
proINDY is the acetylated derivative prodrug of INDY, which is a potent, selective and ATP-competitive inhibitor of Dyrk1A, effectively recovers Xenopus embryos from head malformation induced by Dyrk1A overexpression. |
| PC-22436 |
INDY
DYRK1A inhibitor
|
INDY is a potent, selective and ATP-competitive inhibitor of Dyrk1A withIC50 and Ki values of 0.24 and 0.18 μM, respectively. |
| PC-21660 |
Y020-3945
DYRK1A inhibitor
|
Y020-3945 is a selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor with IC50 of 0.53 uM. |
| PC-21506 |
Leucettinib-21
CLK/DYRK inhibitor
|
Leucettinib-21 is a potent, selective DYRKs and CLKs kinases with IC50 of 2.4, 6.7, 12, 33, and 5 nM for DYRK1A, DYRK1B, CLK1, CLK2, and CLK4, respectively. |
| PC-21496 |
EHT 1610
DYRK1A inhibitor
|
EHT 1610 is a potent inhibitor of DYRKs family kinases with IC50s of 0.36 nM (DYRK1A), 0.59 nM (DYRK1B), respectively. |
| PC-21495 |
FC162
DYRK1A inhibitor
|
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively. |
