| Cat. No. |
Product Name |
Information |
| PC-42939 |
AZ191
DYRK1B inhibitor
|
AZ191 is a potent, selective DYRK1B inhibitor with IC50 of 17 nM, displays 10-fold selectivity over DYRK1A and no activity against DYRK2 (IC50=1890 nM). |
| PC-61025 |
Leucettine L41
CLK/DYRK inhibitor
|
Leucettine L41 is a novel potent cdc2-like kinase (CLKs) and DYRKs inhibitor with IC50 of 40, 35 and 15 nM for DYRK1A, DYRK2 and CLK1, respectively. |
| PC-42167 |
TBID
HIPK2 inhibitor
|
tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM. |
| PC-25697 |
MU135
HIPK inhibitor
|
MU135 is a potent, highly selective Homeodomain-interacting protein kinases (HIPKs) inhibitor with IC50 of 248/119/476 nM for HIPK1/HIPK12/HIPK13, repectively. |
| PC-25696 |
XRF-1021
HIPK2 inhibitor
|
XRF-1021 is a potent inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with IC50 of 0.18 uM, suppresses HIPK2 and blocks TGF-β/Smad3, NF-κB, Wnt/β-catenin, and Notch signaling. |
| PC-25353 |
DYRK1A/1B inhibitor 8h
DYRK1A/DYRK1B inhibitor
|
DYRK1A/1B inhibitor 8h is a potent, selective DYRK1A/DYRK1B inhibitor with IC50 of 5 nM and 3 nM respectively. |
| PC-25352 |
KS-40070
DYRK1B inhibitor
|
KS-40070 is a potent, selective inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1B (DYRK1B) with IC50 of 18 nM, with no inhibition on human DYRK2 (IC50>10 uM). |
| PC-23759 |
SM15685
DYRK1A/B inhibitor
|
SM15685 is a highly selective and potent, oral, brain-penetrant DYRK1A/B inhibitor with IC50 of 1 nM (DYRK1A). |
| PC-23472 |
GSK626616
DYRK3 inhibitor
|
GSK626616 is a potent, orally bioavailable inhibitor of DYRK3 with IC50 of 0.7 nM, inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency. |
| PC-23353 |
NSC361563
DYRK1A inhibitor
|
NSC361563 is a potent and selective DYRK1A inhibitor with IC50 of 1.38 uM. |
| PC-23236 |
DYR530
DYRK1 inhibitor
|
DYR530 is a potent, selective inhibitor of DYRK1 with Kd of 0.91 nM (DYRK1A). |
| PC-23235 |
DYR533
DYRK1 inhibitor
|
DYR533 is a potent, selective inhibitor of DYRK1 with Kd of 1.4 nM (DYRK1A), blocks mnb phosphorylation of human Tau expressed in Drosophila neurons. |
