| Cat. No. |
Product Name |
Information |
| PC-73232 |
Dynein inhibitor 20
Dynein inhibitor
|
Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains. |
| PC-62399 |
Dynarrestin
Dynein inhibitor
|
Dynarrestin is a novel inhibitor of cytoplasmic Dyneins 1 and 2, acts reversibly to inhibit cytoplasmic dynein 1-dependent microtubule binding and motility in vitro without affecting ATP hydrolysis. |
| PC-62398 |
Ciliobrevin D
Dynein inhibitor
|
Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of AAA+ ATPase cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking. |
| PC-62397 |
Dynein2-IN-37
Dynein 2 inhibitor
|
Dynein2-IN-37 (Ciliobrevin analog 37) is a potent, selective cytoplasmic dynein 2 ATPase activity antagonist with IC50 of 11 uM, shows weak inhibition for dynein 2 (IC50=280 uM). |
| PC-42258 |
Ciliobrevin A
Hedgehog inhibitor, Dynein inhibitor
|
Ciliobrevin A (HPI-4) is a small molecule Hedgehog pathway inhibitor (IC50=7 uM) that acts downstream of Su(fu) to modulate Gli processing, activation or trafficking, inhibits AAA+ ATPase motor cytoplasmic dynein. |
