| Cat. No. |
Product Name |
Information |
| PC-25245 |
STA-013
pan-EphB inhibitor
|
STA-013 is a potent, selective pan-EphB tyrosine kinase inhibitor with IC50 of 0.69, 1.73 and 1.02 uM for EphB1, EphB2 and EphB4 respectively. |
| PC-22284 |
CDD-2693
Ephrin receptor inhibitor
|
CDD-2693 (CDD2693) is a potent, selective pan-ephrin receptor kinase (EPH receptor) inhibitor with binding Ki of 4.0/0.81 nM for EPHA2/EPHA4, respectively. |
| PC-22283 |
CDD-3167
Ephrin receptor inhibitor
|
CDD-3167 (CDD3167) is a potent, selective pan-ephrin receptor kinase (EPH receptor) inhibitor with binding Ki of 0.13/0.38 nM, cell IC50 of 8.0/2.3 nM for EPHA2/EPHA4, respectively. |
| PC-49438 |
Targefrin
EphA2-LBD inhibitor
|
Targefrin is a potent, selective antagonist targeting ligand binding domain of receptor tyrosine kinase EphA2 (EphA2-LBD), binds to EphA2-LBD with Kd of 21 nM (ITC) and shows IC50 value of 10.8 nM in biochemical assays. |
| PC-35435 |
UniPR1331
Eph-ephrin inhibitor
|
UniPR1331 (UniPR-1331) is a selective, orally available antagonist of Eph/ephrin interaction with pIC50 of 5.45, IC50 of 2.9 uM. |
| PC-43438 |
NVP-BHG712
EphB4 inhibitor
|
NVP-BHG712 (BHG712) is a potent, specific inhibitor of EphB4 kinase that inhibits EphB4 autophosphorylation with IC50 of 25 nM in cell-bases assays, displays little to no activity against VEGFR2, IGF1R and InsR. |
| PC-62858 |
EphB3-IN-1
EphB3 inhibitor
|
EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM. |
| PC-45397 |
ALW-II-41-27
EPHA2 inhibitor
|
ALW-II-41-27 is a potent, ATP-competitive EPHA2 RTK inhibitor with IC50 of 11 nM. |
| PC-22784 |
UniPR1454
EphA2 inhibitor
|
UniPR1454 is potent and competitive EphA2 receptor antagonist with IC50 of 2.6 uM. |
| PC-21784 |
WCDD301
EphA4 agonist
|
WCDD301 is a high-affinity, orally available agonist of EphA4 receptor. |
| PC-20805 |
UniPR129
Ephrin Receptor antagonist
|
UniPR129 is a potent, selective Eph/ephrin antagonist, competitively disrupts Eph2A-ephrin-A1 binding (IC50=945 nM, Ki = 345 nM). |
