| Cat. No. |
Product Name |
Information |
| PC-21769 |
Lonafarnib
FTase inhibitor
|
Lonafarnib (SCH 66336) is a potent, orally bioavailable farnesyl protein transferase (FTase, farnesyltransferase) inhibitor with IC50 of 1.9 nM for H-Ras processing in whole cells. |
| PC-73014 |
FGTI-2734
Dual FT-GGT1 inhibitor
|
FGTI-2734 (FGTI2734) is a potent, CAAX tetrapeptide RAS C-terminal mimetic as dual farnesyltransferase (FT) and geranylgeranyltransferase-1 (GGT-1) inhibitor with IC50 of 250 and 520 nM, respectively. |
| PC-35110 |
ABT-100
FTase inhibitor
|
ABT-100 (ABT100) is a highly selective, potent, orally bioavailable inhibitor of farnesyltransferase (FTase). |
| PC-63362 |
LB42908
FTase inhibitor
|
LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras.. |
| PC-42625 |
Tipifarnib S enantiomer
|
Tipifarnib S enantiomer is a potent and selective inhibitor of FTase (farnesyltransferase). |
| PC-42624 |
Tipifarnib
FTase inhibitor
|
Tipifarnib ((IND 58359, R115777) is a potent and selective inhibitor of FTase (farnesyltransferase) with IC50 of 0.86 nM. |
| PC-44767 |
FTI-277 hydrochloride
|
FTI-277 hydrochloride is a peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM. |
| PC-44766 |
FTI-277
FTase inhibitor
|
FTI-277 is a peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM. |
| PC-23307 |
A-176120
FTase inhibitor
|
A-176120 is a potent, selective inhibitor of farnesyltransferase (FTase) with IC50 of 1.2 nM, inhibits Ras processing in H-ras-transformed NIH3T3 cells and HCT116 K-ras-mutated cells (ED50=1.6 and 0.5 uM, respectively). |
| PC-22630 |
FTI-2148
FTase inhibitor
|
FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I. |
| PC-22629 |
FTI-2153
FTase inhibitor
|
FTI-2153 is the methylester prodrug of FTI-2148, a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM. |
