| Cat. No. |
Product Name |
Information |
| PC-43538 |
Exenatide
GLP-1 agonist
|
Exenatide (Exendin-4) is a 39-aa peptide, highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM. |
| PC-43093 |
LGD-6972
GCGR antagonist
|
LGD-6972 (RVT 1502) is a novel potent, selective, orally bioavailable glucagon receptor (GCGR) antagonist. |
| PC-61363 |
Apraglutide
GLP-2 analog
|
A peptidic glucagon like peptide 2 (GLP-2) analogue for treatment of type2 diabetes.. |
| PC-70259 |
GLP1 agonist 1
GLP1 agonist
|
GLP1 agonist 1 is a potent, selective GLP-1 receptor agonist with EC50 of 1.4 uM in cAMP functional assays. |
| PC-70258 |
GLP1 agonist 2
|
GLP1 agonist 2 potent, selective GLP-1 receptor agonist with EC50 of 101 nM. |
| PC-70055 |
MK-3577
GCGR antagonist
|
MK-3577 is a potent, oral active glucagon receptor antagonist blocking the glucagon effect for the treatment of T2DM. |
| PC-70024 |
PF-06372222
Glucagon receptor NAM
|
PF-06372222 is a potent glucagon receptor (GCGR) negative allosteric modulator. |
| PC-70023 |
NNC-0640
Glucagon receptor NAM
|
NNC-0640 (NNC 0640, NNC0640) is a potent, selective glucagon receptor (GCGR) negative allosteric modulator with IC50 of 69.2 nM. |
| PC-47502 |
Taspoglutide
GLP-1R agonist
|
Taspoglutide (ITM-077, R-1583, BIM-51077) is a glucagon-like peptide-1(GLP-1) agonist with EC50 of 0.06 nM, shows potential for treatment of type 2 diabetes. |
| PC-47501 |
Lixisenatide
GLP-1 agonist
|
Lixisenatide (ZP10A) is a peptide glucagon-like peptide 1 (GLP-1) receptor agonist. |
| PC-45831 |
MK-0893
Glucagon receptor antagonist
|
A potent, selective, reversible and competitive antagonist of glucagon receptor with high binding affinity (IC(=50=6.6 nM) and functional cAMP activity (IC50=15.7 nM). |
| PC-45745 |
Adomeglivant
GCGR antagonist
|
Adomeglivant (LY-2409021) is a potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM. |
